![]() 25(OH)D is released into the circulation and is transported to the kidney where it undergoes further hydroxylation to 1,25-dihydroxyvitamin D (1,25(OH)D). Vitamin D3 is transported to the liver and is converted to 25-hydroxyvitamin D (25(OH)D). Vitamin D from supplements can be ingested as vitamin D2 from plant sources or vitamin D3 from animal sources. ![]() Two independent pathways lead to vitamin D synthesis: the photochemical action of solar ultraviolet B (UVB) light in the skin and specific dietary sources. ![]() Vitamin D deficiency and insufficiency in patients with asthma and allergic diseases have also recently been discussed. The function of vitamin D, traditionally associated with calcium and phosphate homeostasis, is thought to be highly complex, and its potential roles in cardiovascular, neoplastic, and microbial infections and autoimmune diseases have been investigated in recent studies. ![]() Vitamin D (also known as cholecalciferol) is an active steroid hormone. ![]()
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